POLYMERIC NANOPARTICLES CONJUGATE A NOVEL HEPTAPEPTIDE AS AN EPIDERMAL GROWTH FACTOR RECEPTOR-ACTIVE TARGETING LIGAND FOR DOXORUBICIN

Polymeric nanoparticles conjugate a novel heptapeptide as an epidermal growth factor receptor-active targeting ligand for doxorubicin

COLOR REMOVER Chia Wen Liu,1,2 Wen Jen Lin11Graduate Institute of Pharmaceutical Sciences, College of Medicine, National Taiwan University, Taipei; 2Drug Delivery Department, Biomedical Engineering Research Laboratories, Industrial Technology Research Institute, Hsinchu, TaiwanBackground: This study was performed to develop a functional poly(D,L-la

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Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever.

The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear.We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong activation of antigen-presenting cells (APC), including type I IFN production, observed in response to

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